Steroids in pediatric kidney transplantation: a balancing act in progress.

Interest in minimizing corticosteroid exposure is widespread given the potential associated morbidity. This morbidity may be greater in children where the hope for a lifetime of transplant benefit has been historically linked to the risks of long-term corticosteroids. Corticosteroids also compromise growth, a unique concern in children. Contrasting the potential benefit of less steroid exposure is the potential risk for increased rates of rejection and graft loss. Balancing all risks and benefits is critical.